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Morton Coleman Selected Research

parsaclisib

12/2023Safety and efficacy of parsaclisib in combination with obinutuzumab and bendamustine in patients with relapsed or refractory follicular lymphoma (CITADEL-102): A phase 1 study.
8/2023Parsaclisib, a PI3Kδ inhibitor, in relapsed and refractory mantle cell lymphoma (CITADEL-205): a phase 2 study.
1/2021Phase 2 study of parsaclisib (INCB050465), a highly selective, next-generation PI3Kδ inhibitor, in relapsed or refractory diffuse large B-cell lymphoma (CITADEL-202).

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Morton Coleman Research Topics

Disease

28Lymphoma (Lymphomas)
11/2023 - 02/2002
25Non-Hodgkin Lymphoma (Lymphosarcoma)
02/2015 - 08/2002
22Multiple Myeloma
12/2021 - 01/2002
17Neoplasms (Cancer)
08/2023 - 09/2003
12Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
08/2023 - 09/2005
12Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
01/2021 - 08/2004
9B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
01/2021 - 10/2006
8Disease Progression
10/2022 - 09/2002
6Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
12/2023 - 08/2005
5Waldenstrom Macroglobulinemia (Macroglobulinemia)
02/2023 - 09/2002
5B-Cell Lymphoma (Lymphoma, B Cell)
12/2018 - 08/2005
5Hodgkin Disease (Hodgkin's Disease)
09/2014 - 08/2002
2Thrombocytopenia (Thrombopenia)
12/2023 - 01/2018
2Diarrhea
01/2021 - 01/2018
2Marginal Zone B-Cell Lymphoma (MALT Lymphoma)
01/2021 - 10/2005
2Myelodysplastic Syndromes (Myelodysplastic Syndrome)
01/2015 - 08/2007
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2015 - 08/2007
2Infections
02/2008 - 12/2006
2Thrombosis (Thrombus)
12/2007 - 09/2002
1Neutropenia
12/2023
1Colitis
12/2023
1Exanthema (Rash)
12/2023
1Tonsillar Neoplasms
12/2023
1Headache (Headaches)
01/2021
1Dizziness (Lightheadedness)
01/2021
1Respiratory Tract Infections (Respiratory Tract Infection)
01/2021
1Contusions
01/2021
1Cough
01/2021
1Nausea
05/2019
1Jaundice (Icterus)
05/2019
1Lymphoproliferative Disorders (Lymphoproliferative Disorder)
12/2018
1Lymphomatoid Granulomatosis (Granulomatosis, Lymphomatoid)
12/2018
1Peripheral Nervous System Diseases (PNS Diseases)
01/2018
1Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral)
12/2017
1Melanoma (Melanoma, Malignant)
07/2011
1Graves Ophthalmopathy
09/2010
1Strabismus (Squint)
09/2010

Drug/Important Bio-Agent (IBA)

17Dexamethasone (Maxidex)FDA LinkGeneric
12/2021 - 09/2002
17Rituximab (Mabthera)FDA Link
11/2018 - 04/2003
14Lenalidomide (CC 5013)FDA Link
12/2021 - 09/2007
11Clarithromycin (Biaxin)FDA LinkGeneric
12/2021 - 09/2002
11Monoclonal AntibodiesIBA
01/2015 - 08/2003
10ibrutinibIBA
01/2021 - 07/2013
9Bortezomib (Velcade)FDA Link
01/2018 - 09/2006
9Cyclophosphamide (Cytoxan)FDA LinkGeneric
04/2012 - 02/2005
8Prednisone (Sone)FDA LinkGeneric
04/2012 - 03/2008
7Thalidomide (Thalomid)FDA Link
12/2014 - 01/2002
6epratuzumabIBA
11/2008 - 08/2003
5Agammaglobulinaemia Tyrosine KinaseIBA
11/2023 - 01/2017
5Melphalan (Alkeran)FDA LinkGeneric
12/2019 - 08/2006
5Etoposide (VP 16)FDA LinkGeneric
08/2012 - 03/2008
4Procarbazine (Matulane)FDA Link
04/2012 - 03/2008
4IodineIBA
02/2007 - 12/2004
3Bendamustine HydrochlorideFDA Link
12/2023 - 05/2013
3parsaclisibIBA
12/2023 - 01/2021
3zanubrutinibIBA
11/2023 - 12/2021
3Adrenal Cortex Hormones (Corticosteroids)IBA
12/2021 - 04/2003
3carfilzomibIBA
12/2021 - 01/2016
3Proteasome InhibitorsIBA
12/2021 - 02/2011
3tositumomab I-131 (Bexxar)FDA Link
02/2015 - 10/2005
3Doxorubicin (Adriamycin)FDA LinkGeneric
06/2014 - 12/2010
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
04/2014 - 10/2006
3ORALIT (ORS)IBA
04/2012 - 08/2004
3Vincristine (Oncovin)FDA LinkGeneric
02/2011 - 06/2010
2acalabrutinibIBA
10/2022 - 01/2021
2pomalidomideIBA
01/2019 - 05/2014
2Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA
01/2016 - 02/2013
2Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA
04/2014 - 10/2006
2fludarabineIBA
08/2006 - 08/2005
1obinutuzumabIBA
12/2023
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
12/2023
1Alanine Transaminase (SGPT)IBA
12/2023
1Biomarkers (Surrogate Marker)IBA
11/2020
1Methotrexate (Mexate)FDA LinkGeneric
12/2018
1PanobinostatIBA
01/2018
1ofatumumabFDA Link
01/2017
1Biosimilar PharmaceuticalsIBA
04/2016
1milatuzumabIBA
01/2015
1Dacarbazine (DIC)FDA LinkGeneric
06/2014
1Bleomycin (Blenoxane)FDA LinkGeneric
06/2014
1Vinblastine (Vinblastine Sulfate)FDA Link
06/2014
1Bevacizumab (Avastin)FDA Link
04/2014
1Immunoglobulin M (IgM)IBA
02/2013
1Cisplatin (Platino)FDA LinkGeneric
08/2012
1IfosfamideFDA LinkGeneric
08/2012
1AntigensIBA
07/2011

Therapy/Procedure

33Therapeutics
10/2022 - 02/2002
17Drug Therapy (Chemotherapy)
01/2021 - 08/2002
5Stem Cell Transplantation
12/2019 - 08/2006
5Radioimmunotherapy
02/2015 - 08/2005
3Immunotherapy
01/2021 - 08/2003
3Radiotherapy
01/2021 - 12/2006
3Immunomodulation
03/2013 - 08/2006
3Combination Drug Therapy (Combination Chemotherapy)
04/2012 - 03/2008
2Organ Transplantation
12/2018 - 08/2006
2Transplantation
12/2017 - 08/2006
2Hematopoietic Stem Cell Mobilization
03/2013 - 07/2008
2Splenectomy
04/2008 - 04/2003
1Biological Therapy
11/2015
1Induction Chemotherapy
01/2015